The “Perimenopause Plant” Formula Designed For Quick Relief Against Moody Days & Sweaty Nights

 83% Reduction In Hot Flashes Over Just 12 Weeks → 100% Hormone-Free, Stimulant-Free 

CalmAgain™️ | Hot Flash, Mood, and Night Sweat Relief

Rated 4.7 out of 5
Based on 38 reviews

Per Bottle: 30 Easy-To-Swallow Tablets | 30 Days Supply | $1.97 Per Serving

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  • Reduce intensity and frequency of hot flashes and night sweats within 12 weeks
  • Formulated with the same ingredient strain, dosage, and efficacy used in clinical studies
  • Jointly formulated with a Naturopathic Doctor (ND)

CalmAgain Helps Women Of All Ages Soothe The Symptoms of Low Estrogen

NO MORE HOT FLASHES

80% of American women will experience hot flashes when they enter menopause. CalmAgain’s thermoregulation formula helps to significantly reduce hot flashes, allowing you to wear your favorite outfits again and keep your cool throughout the day

No More Mood Swings

Whether it’s anxiety, depression, bouts of rage, or even sudden crying spells brought on by hormonal imbalance, CalmAgain helps support your estrogen levels with natural mood-enhancing ingredients so you can return to a happier, healthier you.

NO More Night Sweats

CalmAgain’s formula is specifically designed to help shield you from night sweat flare-ups so you can quit changing your pajamas in the middle of the night, burning through your AC bill, or wasting money on cooling aids.

Hundreds of Women Are Waving GOODBYE To Hot Flashes, Mood Swings, And Night Sweats With CalmAgain

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“I would get hot flashes where my face would actually drip with sweat and would last for about 5 minutes straight. I’ve tried temperature regulating sheets, taking Evening Primrose and even acupuncture. Since I’ve been taking CalmAgain, it’s completely stopped. CalmAgain results were noticeable and lasting within 30 days. I could actually sleep through the night without kicking off the covers…no sweating! My mood has also improved.”

- Tina V.

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“I’ve tried many different supplements for menopause and honestly found no relief for hot flashes and mood. I’ve tried everything out there and this seems to do the trick for the majority of symptoms. CalmAgain has helped. Way less hot flashes and definitely a better mood. I’m on my second bottle and will continue to purchase. It’s the only thing that has helped me feel like myself again.”

- Joan H.

The Ingredients In CalmAgain Are Backed By Human Clinical Trials For Fast And Effective Menopause Support

CalmAgain’s ingredients are supported by multiple human clinical trials.

And verified by these gold-standard instruments used in clinical research:

Meet The 4 Natural Ingredients That Make Feeling CalmAgain Possible

REDUCES YOUR HOT FLASHES AND ANXIETY:

Menofelis™ Siberian Rhubarb Extract

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Our high-quality rhubarb extract (Menofelis) is flown in straight from Germany.

Menofelis™ attaches to the body’s estrogen receptors naturally and risk-free to mimic estrogen and disperse calming benefits throughout your system.

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Including support for all 11 symptoms on the Menopause Rating Scale:

  • Hot flashes
  • Heart discomfort
  • Sleep problems
  • Depressive mood
  • Irritability
  • Anxiety
  • Physical and mental exhaustion
  • Sexual problems
  • Bladder problems
  • Vaginal dryness
  • Joint and muscular discomfort

It can reduce hot flashes up to 83% in just 12 weeks and reduce anxiety levels.

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“After two weeks I realized I only had 2 or 3 hot flashes a day when I usually suffered around 6 or 8 daily. I feel less anxious, I am much calmer, and do not experience explosive or uncontrolled mood swings.”

- Maria C

Click Here To See Menofelis Clinical Trial Research

Menofelis TM 's efficacy is backed by:

CLINICAL TRIAL #1:1

**Using conventional hormone therapy only reduces the frequency of hot flashes by about 75%2


CLINICAL TRIAL #2:3

By the end, all women had on average less than 1.4 slight hot flushes per day.


CLINICAL TRIAL #3:4

Siberian rhubarb extract produced a 66% reduction in total scores on the Hamilton Anxiety Scale. A reduction in the severity of anxiety from "moderate" or "severe" to "slight" was also observed.

SUPPORTS YOUR SLEEP AND NIGHT SWEATS:

Sage (Low Thujone or Thuone-Free)

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The phytoestrogens in sage bind to your estrogen receptors to help your body control its temperature better as estrogen levels lower in menopause.

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Meaning no more changing sticky pajamas in the middle of the night, or feeling like you've wet the bed.

Sage has been clinically proven to cut night sweats down by 64% in just 8 weeks.

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“I have absolutely seen a huge change in the amount of hot flashes and night sweats I was experiencing before taking Calm Again! Calm Again has basically eliminated those for me now. It's been amazing to be able to sleep so much better at night!”

- Vicky A.

Click Here To See Sage Clinical Trial Research

Sage's efficacy is backed by:

CLINICAL TRIAL #1:5


CLINICAL TRIAL #2:6


CLINICAL TRIAL #3:7

INCREASES YOUR LIBIDO AND MOOD:

Saffron Extract

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Saffron can help with sexual function, libido, and depressed moods by supporting healthy serotonin and dopamine levels in the body.8

Saffron has been shown to help decrease sex-related pain in just 4 weeks, while increasing both arousal and lubrication.

It can also make a difference in low mood, such as hormonal depression, in 4 weeks.

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“I've noticed I am calmer. I get anxious often, and it seems to be less now. Mood swings are a lot better now!”

- Karin L.

Click Here To See Saffron Clinical Trial Research

Saffron's efficacy is backed by:

CLINICAL TRIAL #1:9

***Saffron was also found to be effective in the treatment of mild to moderate depression, similar to the effects of antidepressant drug, fluoxetine.10


CLINICAL TRIAL #2:11


CLINICAL TRIAL #3:12

In a review of five total studies, saffron supplements were significantly more effective than placebos at treating symptoms of mild-to-moderate depression.

FOR HEALTHY HAIR AND OXIDATIVE STRESS:

Vitamin E (d-alpha-tocopherol)

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Vitamin E acts as a shield against oxidative stress to support a healthy scalp and set the scene for healthy hair growth.13

When you use Vitamin E, it swoops in and fights off those harmful elements, making sure your head is the perfect environment to grow strong, beautiful hair.

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***(CalmAgain also features Calcium and Phosphorus which are critical minerals that contribute to hair health.)

Vitamin E has even been shown to help reduce hot flashes in just 8 weeks and help balance hormones.

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“I am unable to do hormone therapy. CalmAgain has helped tremendously - Less hot flashes. I wanted a natural product that would get my estrogen levels where they should be.

- Susan P.

Click Here To See Vitamin E Clinical Trial Research

Vitamin E's efficacy is backed by:

CLINICAL TRIAL #1:14

CalmAgain Customers Have Reported Experiencing Positive Results Within 90 Days Like:

Feel calmer and less anxious

Feel chilled throughout the day

No more major mood swings

Reduced daily hot flashes and night sweats

Better mood and more confidence

Sleeping through the night again

CalmAgain Is The Fastest Way To Prepare Yourself During Perimenopause And Get Out Of The ‘Hormonal Mess’

Calmagain intro

1 Easy Addition To Your Morning Routine Can Transform Your Life In Just 12 Weeks

SUGGESTED USE

Each bottle contains a 30-day supply (30 tablets). We recommend taking 1 tablet immediately after waking up in the morning with or without food.

Enjoy the continuous reduction in hot flashes, night sweats, and mood swings in the next 12 weeks.

Experience the life-changing benefits of feeling CalmAgain™ with menopausal symptoms no longer bothering you again.

Additional benefits may include changing bedsheets less often, wearing your favorite clothes again, and spending less on cooling aids or other treatments.😉

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Calmagain intro

Formulated For Quick And Long-Lasting Results

Calmagain intro

Safe & Effective Ingredients

Vegan, Paleo, Keto Friendly

Non-GMO, Non-Hormonal & Stimulant Free

Based On Human Clinical Trials

Hear From 1,000s Of Women Who Have Transformed Their Lives With Better Body Co.

average rating 4.7 out of 5
Based on 38 reviews
  • 5 Stars
    31 Reviews
  • 4 Stars
    5 Reviews
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    1 Review
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  • 1 Star
    1 Review
95% of reviewers would recommend this product to a friend
Results
Rated 4 out of 5
Improved Health
Rated 4 out of 5
Overall Satisfaction
Rated 4 out of 5
38 Reviews
Reviewed by Heather M., from United States
Verified Buyer
I recommend this product
Age Range
45 - 54
Gender
Female
My Results
  • Better Sleep
  • Reduced Hot Flashes
  • Better Mood
Been Using For
1 To 2 Months
Rated 5 out of 5
Review posted

No More Night Sweats!

Dramatically reduced the horrible night sweats! This is by far the only thing that has helped. I'm so thankful I found this product.

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Results
Rated 5 out of 5
Improved Health
Rated 3 out of 5
Overall Satisfaction
Rated 5 out of 5
Was this helpful?
Reviewed by Sheila F., from United States
Verified Buyer
Age Range
55 - 64
Gender
Female
My Results
  • Better Digestion
Been Using For
2 to 4 Weeks
Rated 3 out of 5
Review posted

Hoping this product will work

I have started using Calm Again for about 2 weeks now. I haven't experienced great results yet but I'm hoping it will solve my hot flashes issues soon

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Results
Rated 3 out of 5
Improved Health
Rated 3 out of 5
Overall Satisfaction
Rated 2 out of 5
Was this helpful?

Better Body Co.

Hi Sheila,

Thank you for your review. We appreciate your honest feedback about your experience with CalmAgain.

We are sorry to know that you didn't achieve your desired results yet.
It's important to note that individual responses to supplements can vary, and it can sometimes take more time for certain individuals to notice the effects.

We want to let you know that every individual's response to supplements can vary. While on average results are noticed within 6-8 weeks, some customers may require 3 months or longer to achieve all of the desired results, depending on their individual body's reaction.

We encourage you to continue using CalmAgain as recommended and give it a bit more time to see the full range of potential benefits.

Remember that individual experiences with supplements can vary, and it's important to listen to your body and seek professional advice when needed.

If you have any further questions or require additional assistance, please don't hesitate to reach out to our support team at contact@betterbody.co. We are here to support you.

Sincerely,
Nour
Customer Happiness Team
Better Body Co.

Reviewed by Marjorie M., from United States
Verified Buyer
I recommend this product
Age Range
55 - 64
Gender
Female
My Results
  • Increased Metabolism
  • Less Inflammation
Been Using For
1 To 2 Months
Rated 5 out of 5
Review posted

Love it

Loved it

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Results
Rated 5 out of 5
Improved Health
Rated 5 out of 5
Overall Satisfaction
Rated 5 out of 5
Was this helpful?
Reviewed by Astrid A., from Australia
Verified Buyer
I recommend this product
Age Range
45 - 54
Gender
Female
My Results
  • Reduced Hot Flashes
  • Better Sleep
  • Better Mood
  • More Energy
Been Using For
1 To 2 Months
Rated 5 out of 5
Review posted

Best ever

I was sceptical about this supplement BUT after 1 week of taking it every morning, the flushes went away entirely. I slept better. My mood was even. I recommend this supplement to all ladies who are struggling with the change of life.

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Results
Rated 5 out of 5
Improved Health
Rated 5 out of 5
Overall Satisfaction
Rated 5 out of 5
Was this helpful?
Reviewed by Dominique L., from Canada
Verified Buyer
I recommend this product
Age Range
55 - 64
Gender
Female
My Results
  • More Energy
  • Better Mood
  • Improved Skin
  • Less Bloating
  • Weight Loss
Been Using For
1 To 2 Months
Rated 5 out of 5
Review posted

Miss

I am still on my first bottle.. I notice a little difference.. less hot flushes.. and more calm

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Results
Rated 5 out of 5
Improved Health
Rated 5 out of 5
Overall Satisfaction
Rated 5 out of 5
Was this helpful?

Frequently Asked Questions

When can I expect results from CalmAgain?

Clinical studies of key ingredients show that most menopausal symptoms subside after 12-19 weeks.

Does CalmAgain have any side effects?

CalmAgain is not known to have any major side effects.

CalmAgain is made using high-quality, natural ingredients and has been tested safe for consumption. It was formulated to be stimulant-free, which makes it ideal for long-term consumption.

Because of its high potency, some customers may occasionally experience gastrointestinal discomfort or hypersensitivity reactions at the start. This is normal and usually goes away after a few days as your body adjusts.

But if you experience adverse effects, please stop consumption and consult a doctor. If you are on medication or suffer from health conditions, we recommend informing your doctor of your interest in consuming our supplements.

In general, you should follow the recommended dosage of 1 tablet a day. Many customers following this dosage have feedbacked experiencing more sustained effects like fewer hot flashes, night sweats, and mood swings, especially when taken in the long term.

Does CalmAgain contain gluten, soy, peanuts, dairy, shellfish, or any other allergens?

No, CalmAgain does not contain any of these mentioned ingredients or allergens. Because of that, it supports most diets like vegan, keto, paleo, and kosher.

What does Thujone Free Preparation mean?

Sage is naturally rich in thujone, which is toxic to the liver and kidneys. A thujone-free or low thujone preparation would ensure daily intake of thujone would remain below toxicity level.

What if I’m already on HRT?

Many women hesitate to start HRT due to the potential health risks and complications. Others have also mentioned that HRT doesn’t effectively help relieve menopausal symptoms.

If you’re currently already on HRT, it should be safe to consume CalmAgain even when you’re on HRT, as CalmAgain doesn’t affect estrogen levels or other hormones. However, it’s advisable to consult your doctor first before you start taking CalmAgain or if you wish to stop HRT.

Is this a one-time purchase?

Yes, rest assured that all orders on this page are one-time purchases only.

This means that you won’t be charged again in the subsequent months. There will not be any automatic recurring billing or hidden charges.

Once you’ve selected your bottles, you’ll be brought to the checkout page where you can choose to pay by credit card or Paypal.

If you select the PayPal option, you will be brought to the PayPal payment page.

Do you ship worldwide? What are the shipping charges?

Yes, we ship CalmAgain worldwide.

For orders outside the US, the shipping cost depends on the weight of your order, and the updated shipping fee will be shown at checkout.

For orders in the US, we offer free shipping for orders of 2 bottles or more.

What currency are the prices in?

All prices shown are in United States Dollars (USD), but you can purchase outside the US as we ship worldwide.

If you're using non-US currencies, the conversion will be done by your bank or payment provider and they will be reflected in your currency.

When can I expect my shipment of CalmAgain?

Below are the estimated delivery timings.

Expedited Shipping: 2 to 7 business days for orders within the US
Free Regular Shipping: 5 to 18 business days for orders within the US

Upon completion of your order, you’ll receive an email confirmation from us and an estimated delivery time. We’ll inform you if there’s any change to your shipment delivery date.

Can CalmAgain be purchased elsewhere?

We advise customers to avoid purchasing from non-approved vendors. Many counterfeit products are currently been sold online. To ensure you’re getting the genuine product, only purchase CalmAgain directly from our website.

To keep the formula fresh, and as potent as possible, we want to avoid storing it in a warehouse or a store shelf. Instead, we ship your order directly after bottling to your doorstep as fast as possible.

How does the guarantee work?

We’re so sure of the effectiveness of CalmAgain that each order comes with a 90-day money-back guarantee. Try it out for three months and the bottle to see if it works for you.

If you aren’t 100% satisfied with your results, just drop us a message and you’ll be refunded based on our terms and conditions.

How to take CalmAgain? What is the dosage?

For best results, take 1 tablet in the morning daily before breakfast with a glass of water.

What form does CalmAgain come in?

CalmAgain comes in tablet form. Each bottle contains a 30-day supply (30 Tablets).

Do I need to refrigerate CalmAgain?

No refrigeration is needed. Our product is shelf-stable and can last up to 2 years upon delivery.

Kindly store in a cool, dry place to preserve maximum potency.

Where is CalmAgain manufactured?

CalmAgain is manufactured in a GMP-certified, FDA-registered factory located in the USA.

What are the exact ingredients in CalmAgain?

The main ingredients of CalmAgain are Menofelis™ Siberian Rhubarb Extract, Saffron Extract, Sage Extract (low Thujone / Thuone-free preparation), Vitamin E (d-alpha-tocopherol).

For more information on the product, kindly refer to the product label or the ingredients listed above.

Disclaimer

These statements have not been evaluated by the Food and Drug Administration.

This product is not intended to diagnose, treat, cure or prevent any medical conditions.

The testimonials presented apply only to the individuals depicted, cannot be guaranteed, and should not be considered typical.

Every testimonial on this website is from a real customer who used the product, and/or nutrition advice listed on the website.

No one was paid for a testimonial or endorsement. Results were self-reported by the customer. You should assume that any results shown in testimonials, advertisements, stories, blog posts, articles, forums, or anywhere else on this site or our associated websites are not typical. Results may vary from person to person.

References
  1. Chang, J. L., Montalto, M. B., Heger, P. W., Thiemann, E., Rettenberger, R., & Wacker, J. (2016). Rheum rhaponticum Extract (ERr 731): Postmarketing Data on Safety Surveillance and Consumer Complaints. Integrative medicine (Encinitas, Calif.), 15(3), 34–39.
  2. Kaszkin-Bettag, M., Ventskovskiy, B. M., Solskyy, S., Beck, S., Hasper, I., Kravchenko, A., Rettenberger, R., Richardson, A., & Heger, P. W. (2009). Confirmation of the efficacy of ERr 731 in perimenopausal women with menopausal symptoms. Alternative therapies in health and medicine, 15(1), 24–34.
  3. Shah, J., Chandanani, S., Reddy, J., Kirubamani, H., Boruah, A. M., Jain, A., Mane, S., Biniwale, P., Mathur, P., Ridhorkar, A., Natarajan, S., & Tiwari, B. (2021). Evaluation of the Efficacy and Safety of Rheum rhaponticum Root Extract (ERr 731) for Menopausal Symptoms in Perimenopausal Indian Women: An Interim Analysis. Journal of mid-life health, 12(2), 108–115. https://doi.org/10.4103/jmh.jmh_86_21
  4. Heger, M., Ventskovskiy, B. M., Borzenko, I., Kneis, K. C., Rettenberger, R., Kaszkin-Bettag, M., & Heger, P. W. (2006). Efficacy and safety of a special extract of Rheum rhaponticum (ERr 731) in perimenopausal women with climacteric complaints: a 12-week randomized, double-blind, placebo-controlled trial. Menopause (New Y ork, N.Y .), 13(5), 744–759. https://doi.org/10.1097/01.gme.0000240632.08182.e4
  5. Kaszkin-Bettag, M., Beck, S., Richardson, A., Heger, P. W., & Beer, A. M. (2008). Efficacy of the special extract ERr 731 from rhapontic rhubarb for menopausal complaints: a 6-month open observational study. Alternative therapies in health and medicine, 14(6), 32–38.
  6. Hasper, I., Ventskovskiy, B. M., Rettenberger, R., Heger, P. W., Riley, D. S., & Kaszkin-Bettag, M. (2009). Long-term efficacy and safety of the special extract ERr 731 of Rheum rhaponticum in perimenopausal women with menopausal symptoms. Menopause (New York, N.Y.), 16(1), 117–131. https://doi.org/10.1097/GME.0b013e3181806446
  7. Kashani, L., Esalatmanesh, S., Eftekhari, F., Salimi, S., Foroughifar, T., Etesam, F., Safiaghdam, H., Moazen-Zadeh, E., & Akhondzadeh, S. (2018). Efficacy of Crocus sativus (saffron) in treatment of major depressive disorder associated with post- menopausal hot flashes: a double-blind, randomized, placebo-controlled trial. Archives of gynecology and obstetrics, 297(3), 717– 724. https://doi.org/10.1007/s00404-018-4655-2
  8. Lopresti, A. L., & Smith, S. J. (2021). The Effects of a Saffron Extract (affron®) on Menopausal Symptoms in Women during Perimenopause: A Randomised, Double-Blind, Placebo-Controlled Study. Journal of menopausal medicine, 27(2), 66–78. https://doi.org/10.6118/jmm.21002
  9. Ziaei, S., Kazemnejad, A., & Zareai, M. (2007). The effect of vitamin E on hot flashes in menopausal women. Gynecologic and obstetric investigation, 64(4), 204–207. https://doi.org/10.1159/000106491
  10. Ataei-Almanghadim, K., Farshbaf-Khalili, A., Ostadrahimi, A. R., Shaseb, E., & Mirghafourvand, M. (2020). The effect of oral capsule of curcumin and vitamin E on the hot flashes and anxiety in postmenopausal women: A triple blind randomised controlled trial. Complementary therapies in medicine, 48, 102267. https://doi.org/10.1016/j.ctim.2019.102267
  11. Yousefi-Nodeh, H., Farshbaf-Khalili, A., Sadeghzadeh Oskouei, B., Jafarilar-Aghdam, N., Kazemi-Zanjani, N., & Pourzeinali, S. (2022). Curcumin and vitamin E improve hot flashes, lipid profile, and fasting blood glucose without any detrimental effect on the liver and renal function in postmenopausal women: A triple-blind placebo-controlled clinical trial. Health care for women international, 1– 23. Advance online publication. https://doi.org/10.1080/07399332.2022.2117815
  12. Bommer, S., Klein, P., & Suter, A. (2011). First time proof of sage's tolerability and efficacy in menopausal women with hot flushes. Advances in therapy, 28(6), 490–500. https://doi.org/10.1007/s12325-011-0027-z
  13. Zeidabadi, A., Yazdanpanahi, Z., Dabbaghmanesh, M. H., Sasani, M. R., Emamghoreishi, M., & Akbarzadeh, M. (2020). The effect of Salvia officinalis extract on symptoms of flushing, night sweat, sleep disorders, and score of forgetfulness in postmenopausal women. Journal of family medicine and primary care, 9(2), 1086–1092. https://doi.org/10.4103/jfmpc.jfmpc_913_19
  14. Dadfar, F., & Bamdad, K. (2019). The effect of Saliva officinalis extract on the menopausal symptoms in postmenopausal women: An RCT. International journal of reproductive biomedicine, 17(4), 287–292. https://doi.org/10.18502/ijrm.v17i4.4555
  15. Lachenmeier, D. W., & Uebelacker, M. (2010). Risk assessment of thujone in foods and medicines containing sage and wormwood--evidence for a need of regulatory changes?. Regulatory toxicology and pharmacology : RTP, 58(3), 437–443. https://doi.org/10.1016/j.yrtph.2010.08.012
  16. https://www.avogel.co.uk/herbal-remedies/sage-herb-menosan/
  17. https://www.ema.europa.eu/en/documents/scientific-guideline/public-statement-use-herbal-medicinal-products-containing-thujone- revision-1_en.pdf
  18. Coombs, N., Taylor, R., Wilcken, N., Fiorica, J., & Boyages, J. (2005). Hormone replacement therapy and breast cancer risk in california. The Breast Journal, 11(6), 410-415. https://doi.org/10.1111/j.1075-122x.2005.00132.x
  19. Chen, J., Guo, Q., Pei, Y., Ren, Q., Chi, L., Hu, R., … & Tan, Y. (2020). Effect of a short-term vitamin e supplementation on oxidative stress in infertile pcos women under ovulation induction: a retrospective cohort study. BMC Women S Health, 20(1). https://doi.org/10.1186/s12905-020-00930-w
  20. Sadeghi, A., Ghahari, L., & Yousefpour, M. (2019). Vitamin e supplementation reduces oxidative stress in the male wistar rats’ brain against polyvinyl chloride products. Annals of Military and Health Sciences Research, 17(2). https://doi.org/10.5812/amh.92768
  21. Liudvytska, O. and Kolodziejczyk-Czepas, J. (2022). A review on rhubarb-derived substances as modulators of cardiovascular risk factors—a special emphasis on anti-obesity action. Nutrients, 14(10), 2053. https://doi.org/10.3390/nu14102053
  22. Zhang, Z., Li, M., Liu, D., Chen, H., Chen, D., Tan, N., … & Zhao, Y. (2018). Rhubarb protect against tubulointerstitial fibrosis by inhibiting tgf-β/smad pathway and improving abnormal metabolome in chronic kidney disease. Frontiers in Pharmacology, 9. https://doi.org/10.3389/fphar.2018.01029
  23. Ettehadi, H., Mojabi, S., Ranjbaran, M., Shams, J., Sahraei, H., Hedayati, M., … & Asefi, F. (2013). Aqueous extract of saffron (<i>crocus sativus</i>) increases brain dopamine and glutamate concentrations in rats. Journal of Behavioral and Brain Science, 03(03), 315-319. https://doi.org/10.4236/jbbs.2013.33031
  24. Oliveira, C., Pourtau, L., Vancassel, S., Pouchieu, C., Capuron, L., Gaudout, D., … & Castanon, N. (2021). Saffron extract-induced improvement of depressive-like behavior in mice is associated with modulation of monoaminergic neurotransmission. Nutrients, 13(3), 904. https://doi.org/10.3390/nu13030904
  25. Pachikian, B., Copine, S., Suchareau, M., & Deldicque, L. (2021). Effects of saffron extract on sleep quality: a randomized double-blind controlled clinical trial. Nutrients, 13(5), 1473. https://doi.org/10.3390/nu13051473
  26. Kennedy, D., Dodd, F., Robertson, B., Okello, E., Reay, J., Scholey, A., … & Haskell, C. (2010). Monoterpenoid extract of sage (salvia lavandulaefolia) with cholinesterase inhibiting properties improves cognitive performance and mood in healthy adults. Journal of Psychopharmacology, 25(8), 1088-1100. https://doi.org/10.1177/0269881110385594
  27. Lima, C., Valentão, P., Andrade, P., Seabra, R., Fernandes-Ferreira, M., & Pereira-Wilson, C. (2007). Water and methanolic extracts of salvia officinalis protect hepg2 cells from t-bhp induced oxidative damage. Chemico-Biological Interactions, 167(2), 107-115. https://doi.org/10.1016/j.cbi.2007.01.020
  28. Pinkerton, J., Aguirre, F., Blake, J., Cosman, F., Hodis, H., Hoffstetter, S., … & Utian, W. (2017). The 2017 hormone therapy position statement of the north american menopause society. Menopause the Journal of the North American Menopause Society, 24(7), 728-753. https://doi.org/10.1097/gme.0000000000000921
  29. https://www.metagenicsinstitute.com/wp-content/uploads/2018/01/MET2390-Estrovera-Science-Review_MI.pdf
  30. Mazidi M, Shemshian M, Mousavi SH, Norouzy A, Kermani T, Moghiman T, Sadeghi A, Mokhber N, Ghayour-Mobarhan M, Ferns GA. A double-blind, randomized and placebo-controlled trial of Saffron (Crocus sativus L.) in the treatment of anxiety and depression. J Complement Integr Med. 2016 Jun 1;13(2):195-9. doi: 10.1515/jcim-2015-0043. PMID: 27101556.
  31. Kashani L, Esalatmanesh S, Eftekhari F, Salimi S, Foroughifar T, Etesam F, Safiaghdam H, Moazen-Zadeh E, Akhondzadeh S. Efficacy of Crocus sativus (saffron) in treatment of major depressive disorder associated with post-menopausal hot flashes: a double-blind, randomized, placebo-controlled trial. Arch Gynecol Obstet. 2018 Mar;297(3):717-724. doi: 10.1007/s00404-018-4655-2. Epub 2018 Jan 13. PMID: 29332222.
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